Publications

  1. Fleming J, Marvel S, Motsinger-Reif A, Reif DM. 2021. ToxPi*GIS Toolkit: creating, viewing, and sharing integrative visualizations for geospatial data using ArcGIS. medRxiv: The Preprint Server for Health Sciences. doi:10.1101/2021.10.08.21264756 PMID:34671776 PMCID:PMC8528084
  2. Cohen Hubal EA, DeLuca NM, Mullikin A, Slover R, Little JC, Reif DM. 2022. Demonstrating a systems approach for integrating disparate data streams to inform decisions on children’s environmental health. BMC Public Health. 22(1):313. doi:10.1186/s12889-022-12682-3 PMID:35168583 PMCID:PMC8845296
  3. Kofeler HC, Ahrends R, Baker ES, Ekroos K, Han X, Hoffmann N, Holcapek M, Wenk MR, Liebisch G. 2021. Recommendations for good practice in MS-based lipidomics. Journal of Lipid Research. 62:doi:10.1016/j.jlr.2021.100138 PMID:34662536 PMCID:PMC8585648
  4. Kirkwood KI, Christopher MW, Burgess JL, Littau S, Foster K, Richey K, Pratt BS, Shulman N, Tamura K, MacCoss MJ, MacLean BX, Baker ES. 2021. Development and application of multidimensional lipid libraries to investigate lipidomic dysregulation related to smoke inhalation injury severity. Journal of Proteome Research. doi:10.1021/acs.jproteome.1c00820 PMID:34874736 PMCID:PMC8741653
  5. Khadempour L, Kyle JE, Webb-Robertson B, Nicora CD, Smith FB, Smith RD, Lipton MS, Currie CR, Baker ES, Burnum-Johnson KE. 2021. From plants to ants: fungal modification of leaf lipids for nutrition and communication in the leaf-cutter ant fungal garden ecosystem. mSystems. 6(2):e013070-20. doi:10.1128/mSystems.01307-20 PMID:33758033 PMCID:PMC8547007
  6. Dodds J, Baker ES. 2021. Improving the speed and selectivity of newborn screening using ion mobility spectrometry-mass spectrometry. Analytical Chemistry. 93:17094-17102. doi:10.1021/acs.analchem.1c04267 PMID:34851605 PMCID:PMC8730783
  7. Aly NA, Dodds J, Luo Y, Grimm FA, Foster MR, Rusyn I, Baker ES. 2021. Utilizing ion mobility spectrometry-mass spectrometry for the characterization and detection of persistent organic pollutants and their metabolites. Analytical and Bioanalytical Chemistry. 414(3):doi:10.1007/s00216-021-03686-w PMID:34668045 (ahead of print)
  8. Witchey SK, Doyle MG, Fredenburg JD, Armour GS, Horman BM, Odenkirk MT, Aylor DL, Baker ES, Patisaul HB. 2022. Impacts of gestational FireMaster 550 (FM 550) exposure on the neonatal cortex are sex specific and largely attributable to the organophosphate esters. Neuroendocrinology. doi:10.1159/000526959 PMID:36075192
  9. Foster MR, Rainey M, Watson C, Dodds J, Kirkwood KI, Fernandez FM, Baker ES. 2022. Uncovering PFAS and other xenobiotics in the dark metabolome using ion mobility spectrometry, mass defect analysis, and machine learning. Environmental Science & Technology. 56:doi:10.1021/acs.est.2c00201 PMID:35653285
  10. Enders J, Weed RA, Griffith EH, Muddiman DC. 2022. Development and validation of a high resolving power absolute quantitative per- and polyfluoroalkyl substances method incorporating Skyline data processing. Rapid Communications in Mass Spectrometry : RCM. 36:e9295. doi:10.1002/rcm.9295 PMID:35275435
  11. Butler KE, Dodds J, Flick T, Campuzano ID, Baker ES. 2022. High-resolution demultiplexing (HRdm) ion mobility spectrometry-mass spectrometry for aspartic and isoaspartic acid determination and screening. Analytical Chemistry. doi:10.1021/acs.analchem.1c05533 PMID:35421308
  12. Butler KE, Baker ES. 2022. A high-throughput ion mobility spectrometry-mass spectrometry screening method for opioid profiling. Journal of the American Society for Mass Spectrometry. 33(10):1904-1913. doi:10.1021/jasms.2c00186 PMID:36136315
  13. Evich MG, Davis MJ, McCord JP, Acrey B, Awkerman JA, Knappe D, Lindstrom AB, Speth TF, Tebes-Stevens C, Strynar M, Wang Z, Weber EJ, Henderson WM, Washington JW. 2022. Per- and polyfluoroalkyl substances in the environment. Science (New York, N.Y.). 375:doi:10.1126/science.abg9065 PMID:35113710 PMCID:PMC8902460
  14. Ducatman A, LaPier J, Fuoco RE, DeWitt JC. 2022. Official health communications are failing PFAS-contaminated communities. Environmental Health. doi:10.1186/s12940-022-00857-9 PMID:35538533 PMCID:PMC9092686
  15. McDonough CA, Li W, Bischel HN, De Silva AO, DeWitt JC. 2022. Widening the lens on PFASs: Direct human exposure to perfluoroalkyl acid precursors (pre-PFAAs). Environmental Science & Technology. 56(10):6004-6013. doi:10.1021/acs.est.2c00254 PMID:35324171
  16. T C. Guillette, Thomas Jackson, Matthew P. Guillette, Scott M. Belcher, North Carolina State University; James P. McCord, U.S. Environmental Protection Agency. Blood Concentrations of Per- and Polyfluoroalkyl Substances are Associated with Autoimmune-like Effects in American Alligators from Wilmington, North Carolina. 20 October 2022. Front.Toxicol. 4:1010185. doi: 10.3389/ftox.2022.1010185.
  17. Emma M. Rosen, Nadine Kotlarz, Detleft R.U. Knappe, C. Suzanne Lea, David N. Collier, David B. Richardson, Jane A. Hoppin. Drinking Water–Associated PFAS and Fluoroethers and Lipid Outcomes in the GenX Exposure Study. 7 September 2022 CID: 097002 https://doi.org/10.1289/EHP11033.
  18. Dylan J. Wallis, Kelsey E. Barton, Detlef R.U. Knappe, Nadine Kotlarz, Carrie A. McDonough, Christopher P. Higgins, Jane A. Hoppin, John L. Adgate. Source apportionment of serum PFASs in two highly exposed communities. ScienceDirect. 2022 Sept 22. https://doi.org/10.1016/j.scitotenv.2022.158842.
  19. Belcher SM, Guillette MP, Robb F, Rock KD. Comparative assessment of blood mercury in American alligators (Alligator mississippiensis) from Coastal North Carolina and Florida. Ecotoxicology. 2022 Aug 3. doi: 10.1007/s10646-022-02573-z. Epub ahead of print. PMID: 35918620.
  20. Roell K, Koval LE, Boyles R, Patlewicz G, Ring C, Rider CV, Ward-Caviness C, Reif DM, Jaspers I, Fry RC, Rager JE. Development of the InTelligence And Machine LEarning (TAME) Toolkit for Introductory Data Science, Chemical-Biological Analyses, Predictive Modeling, and Database Mining for Environmental Health Research. Front Toxicol. 2022 Jun 22;4:893924. doi: 10.3389/ftox.2022.893924. PMID: 35812168; PMCID: PMC9257219.16;167:107419. doi: 10.1016/j.envint.2022.107419. Epub ahead of print. PMID: 35863239.
  21. Starnes HM, Rock KD, Jackson TW, Belcher SM. A Critical Review and Meta-Analysis of Impacts of Per- and Polyfluorinated Substances on the Brain and Behavior. Front Toxicol. 2022 Apr 11;4:881584. doi: 10.3389/ftox.2022.881584. PMID: 35480070
  22. Truong L, Rericha Y, Thunga P, Marvel S, Wallis D, Simonich MT, Field JA, Cao D, Reif DM, Tanguay RL. Systematic developmental toxicity assessment of a structurally diverse library of PFAS in zebrafish. J Hazard Mater. 2022 Mar 2;431:128615. doi: 10.1016/j.jhazmat.2022.128615. Epub ahead of print. PMID: 35263707
  23. Bilbao A, Gibbons BC, Stow SM, Kyle JE, Bloodsworth KJ, Payne SH, Smith RD, Ibrahim YM, Baker ES, Fjeldsted JC. A preprocessing tool for enhanced ion mobility-mass spectrometry-based omics workflows. J Proteome Res. 2021 August 12.
  24. Butler KE, Takinami Y, Rainczuk A, Baker ES, Roberts BR. Utilizing ion mobility-mass spectrometry to investigate the unfolding pathway of cu/zn superoxide dismutase. Front Chem. 2021 February 09; 9: 614595. PMCID: PMC7900566.
  25. Zhang, C., McElroy, A. C., Liberatore, H. K., Alexander, N. L. M., & Knappe, D. R. U. (2021). Stability of Per- and Polyfluoroalkyl Substances in Solvents Relevant to Environmental and Toxicological Analysis. Environmental Science & Technology.
  26. Dodds JN, Alexander NLM, Kirkwood KI, Foster MR, Hopkins ZR, Knappe DRU, Baker ES. From pesticides to per- and polyfluoroalkyl substances: An evaluation of recent targeted and untargeted mass spectrometry methods for xenobiotics. Anal Chem. 2021 January 12; 93(1): 641-656. PMCID: PMC7855838.
  27. Enders JR, O’Neill GM, Whitten JL, Muddiman DC. Understanding the electrospray ionization response factors of per- and poly-fluoroalkyl substances (PFAS). Anal Bioanal Chem. 2021 July 21.
  28. Kirkwood KI, Fleming J, Nguyen H, Reif DM, Baker ES, Belcher SM. Utilizing Pine Needles to Temporally and Spatially Profile Per- and Polyfluoroalkyl Substances. bioRxiv 2021 Aug 08; doi: https://doi.org/10.1101/2021.08.24.457570
  29. Gilchrist PO, Alexander AB, Green AJ, Sanders FE, Hooker AQ, Reif DM. Development of a pandemic awareness STEM outreach curriculum: Utilizing a computational thinking taxonomy framework. . Education Sciences. 2021; 11(3): 109. PMCID: PMC8612627
  30. Jackson TW, Scheibly CM, Polera ME, Belcher SM. Rapid characterization of human serum albumin binding for per- and polyfluoroalkyl substances using differential scanning fluorimetry. Environ Sci Technol. 2021 September 21; 55(18): 12291-12301.
  31. Fleming J, Marvel SW, Motsinger-Reif AA, Reif DM. ToxPi*GIS Toolkit: Creating, viewing, and sharing integrative visualizations for geospatial data using ArcGIS. medRxiv. 2021 Oct 12. doi: 10.1101/2021.10.08.21264756.
  32. Marvel SW, House JS, Wheeler M, Song K, Zhou YH, Wright FA, Chiu WA, Rusyn I, Motsinger-Reif A, Reif DM. The COVID-19 pandemic vulnerability index (PVI) dashboard: Monitoring county-level vulnerability using visualization, statistical modeling, and machine learning. Environ Health Perspect. 2021 January 01; 129(1): 17701. PMCID: PMC7785295.
  33. Odenkirk MT, Reif DM, Baker ES. Multiomic big data analysis challenges: Increasing confidence in the interpretation of artificial intelligence assessments. Anal Chem. 2021 May 24. PMCID: PMC8465926.
  34. Wallis DJ, Truong L, La Du J, Tanguay RL, Reif DM. Uncovering evidence for endocrine-disrupting chemicals that elicit differential susceptibility through gene-environment interactions. Toxics. 2021 April 06; 9(4): 10.3390/toxics9040077. PMCID: PMC8067468.
  35. Cohen Hubal EA, Reif DM, Slover R, Mullikin A, Little JC. Children’s environmental health: A systems approach for anticipating impacts from chemicals. Int J Environ Res Public Health. 2020 November 11; 17(22): 10.3390/ijerph17228337. PMCID: PMC7696947.
  36. Gluge J, Scheringer M, Cousins IT, DeWitt JC, Goldenman G, Herzke D, Lohmann R, Ng CA, Trier X, Wang Z. An overview of the uses of per- and polyfluoroalkyl substances (PFAS). Environ Sci Process Impacts. 2020 December 01; 22(12): 2345-2373. PMCID: PMC7784712.
  37. Kwiatkowski, C.F. Andrews, D.Q. Birnbaum, L.S. Bruton, T.A. DeWitt, J.C. Knappe, D.R.U. Maffini, M.V. Miller, M.F. Pelch, K.E. Reade, A. Soehl, A. Trier, X. Venier, M. Wagner, C.C. Wang, Z. Blum, A. Scientific basis for managing PFAS as a chemical class. Environmental Science & Technology Letters. 2020 June 30,; 7(8): 532–543.
  38. Odenkirk MT, Zin PPK, Ash JR, Reif DM, Fourches D, Baker ES. Structural-based connectivity and omic phenotype evaluations (SCOPE): A cheminformatics toolbox for investigating lipidomic changes in complex systems. Analyst. 2020 November 09; 145(22): 7197-7209. PMCID: PMC7695036.
  39. Odenkirk MT, Stratton KG, Gritsenko MA, Bramer LM, Webb-Robertson BM, Bloodsworth KJ, Weitz KK, Lipton AK, Monroe ME, Ash JR, Fourches D, Taylor BD, Burnum-Johnson KE, Baker ES. Unveiling molecular signatures of preeclampsia and gestational diabetes mellitus with multi-omics and innovative cheminformatics visualization tools. Mol Omics. 2020 December 01; 16(6): 521-532. PMCID: PMC7736332.
  40. Dodds JN, Hopkins ZR, Knappe DRU, Baker ES. Rapid Characterization of Per- and Polyfluoroalkyl Substances (PFAS) by Ion Mobility Spectrometry-Mass Spectrometry (IMS-MS). Analytical chemistry. 2020 March 17;92(6):4427-4435. PubMed PMID: 32011866; PubMed Central PMCID: PMC7173758; DOI: 10.1021/acs.analchem.9b05364.